Dr. van der Schyff obtained her specialist qualification as a general surgeon in 2016, at the University of Pretoria, cum laude. She underwent additional training in Paediatric surgery for 2 years before accepting a training post in abdominal transplant surgery at the Wits Donald Gordon Medical Center.

She has since qualified as an abdominal transplant surgeon is currently on the permanent staff complement at the Transplant Unit in Johannesburg and has taken a leading role in the renal transplant unit. Dr van der Schyff has previously published on biliary atresia and necrotizing enterocolitis in children and her current field of research include graft tolerance in children post liver transplant. She is currently serving as an examiner and preparatory course organiser for the ESOT Transplant Surgery examination board and is a member of the Vanguard committee. She served at the 2022 SATS Biennial Congress organising chair and has been elected President elect for the SATS executive committee.